When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Next-generation sequencing (NGS) has made analyzing DNA faster and cheaper, with effects felt in the lab, clinic, and beyond. A set of newly-launched technologies are offering a twist on the chemistry ...

Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore. Since the 1990s, nanopores have been used for ...

Roche has put forward a new approach to genetic analysis, which it describes as sequencing-by-expansion—a proprietary method that pulls apart the DNA molecule and amplifies the signal of each ...

The newest DNA sequencing technology from Swiss multinational Roche doesn’t measure DNA directly but in fact analyzes a different polymer altogether. The technology is not yet available for sale, but ...

With its fast analyses and ultra-long reads, nanopore sequencing has transformed genomics, transcriptomics and epigenomics. Now, thanks to advances in nanopore design and protein engineering, protein ...

While solution-phase chemistry lets millions of parallel DNA reactions be performed simultaneously in a beaker, manipulating single molecules of DNA is still a formidable challenge. A new technique, ...